Pathology of Peripheral Nerve

Pathology of peripheral nerve.

The Pathology of Peripheral Nerve Diseases

Introduction This article will first briefly summarise the structure of the normal peripheral nerve followed by a description of the changes seen when either the axon or the myelin degenerates. Then there is a summary of the clinical features of peripheral neuropathy and the means of investigating them. Next there is a short paragraph on performing the nerve biopsy and what information can be o...

Nanotechnology for peripheral nerve regeneration

Peripheral nerve injuries (PNI) can lead to lifetime loss of function and disfigurement. Different methods such as conventional allograft procedures and using of biological tubes have problems for damaged peripheral nerves reconstruction. Designed scaffolds with natural and synthetic materials are now widely used in the reconstruction of damaged tissues. Utilization of absorbable and non-absorb...

Nanotechnology for peripheral nerve regeneration

Peripheral nerve injuries (PNI) can lead to lifetime loss of function and disfigurement. Different methods such as conventional allograft procedures and using of biological tubes have problems for damaged peripheral nerves reconstruction. Designed scaffolds with natural and synthetic materials are now widely used in the reconstruction of damaged tissues. Utilization of absorbable and non-absorb...

Peripheral nerve and neuromuscular junction pathology in Pompe disease.

Pompe disease is a systemic metabolic disorder characterized by lack of acid-alpha glucosidase (GAA) resulting in ubiquitous lysosomal glycogen accumulation. Respiratory and ambulatory dysfunction are prominent features in patients with Pompe yet the mechanism defining the development of muscle weakness is currently unclear. Transgenic animal models of Pompe disease mirroring the patient phenot...